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What is Risedronate (Actonel)?

RISEDRONATE reduces calcium loss from bones. It helps make healthy bone and to slow bone loss in patients with Paget's disease and osteoporosis. It may be used in others at risk for bone loss.

What should I tell my health care provider before I take Risedronate (Actonel)?

They need to know if you have any of these conditions:

  • dental disease
  • esophagus, stomach, or intestine problems, like acid reflux or GERD
  • kidney disease
  • low blood calcium
  • problems sitting or standing
  • trouble swallowing
  • an unusual or allergic reaction to risedronate, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use Risedronate (Actonel)?

You must take this medication exactly as directed or you will lower the amount of medicine you absorb into your body or you may cause your self harm. Take Risedronate (Actonel) by mouth first thing in the morning, after you are up for the day. Do not eat or drink anything before you take Risedronate (Actonel). Swallow the tablets with a full glass (6 to 8 fluid ounces) of plain water. Do not take the tablets with any other drink. Do not chew or crush the tablet. After taking Risedronate (Actonel), do not eat breakfast, drink, or take any other medicines or vitamins for at least 30 minutes. Stand or sit up for at least 30 minutes after you take Risedronate (Actonel); do not lie down. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of Risedronate (Actonel) in children. Special care may be needed.

Overdosage: If you think you have taken too much of Risedronate (Actonel) contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share Risedronate (Actonel) with others.

What if I miss a dose?

If you miss a dose, do not take it later in the day. Take your normal dose the next morning. Do not take double or extra doses.

What may interact with Risedronate (Actonel)?

  • antacids like aluminum hydroxide or magnesium hydroxide
  • aspirin
  • calcium supplements
  • iron supplements
  • NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
  • thyroid hormones
  • vitamins with minerals

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using Risedronate (Actonel)?

Visit your doctor or health care professional for regular check ups. It may be some time before you see the benefit from Risedronate (Actonel). Your doctor or health care professional may order blood tests and other tests to see how you are doing.

You should make sure you get enough calcium and vitamin D while you are taking Risedronate (Actonel), unless your doctor tells you not to. Discuss the foods you eat and the vitamins you take with your health care professional.

Some people who take Risedronate (Actonel) have severe bone, joint, and/or muscle pain. Tell your doctor if you have pain that does not go away or that gets worse.

What side effects may I notice from Risedronate (Actonel)?

Side effects that you should report to your doctor as soon as possible:

  • allergic reactions such as skin rash or itching, hives, swelling of the face, lips, throat, or tongue
  • black or tarry stools
  • changes in vision
  • heartburn or stomach pain
  • jaw pain, especially after dental work
  • pain or difficulty when swallowing
  • redness, blistering, peeling, or loosening of the skin, including inside the mouth

Side effects that usually do not require medical attention (report to your doctor if they continue or are bothersome):

  • bone, muscle, or joint pain
  • changes in taste
  • diarrhea or constipation
  • eye pain or itching
  • headache
  • nausea or vomiting
  • stomach gas or fullness

This list may not describe all possible side effects.

Where should I keep Risedronate (Actonel)?

Keep out of the reach of children.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Throw away any unused medicine after the expiration date.

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